Serum Lipoproteins in Experimental Diabetes. II. Action of Heparin in vivo on Lipoproteins of Depancreatized Dogs. ∗

Abstract

Summary

Heparin causes a clearing of the lipemic serum of normal and, less, of depancreatized dogs. In normal animals with alimentary hyperlipemia, this clearing is associated with a decrease in the lipid content of the slow-moving lipoprotein fractions, while in the diabetic lipemic dogs, the outstanding change is the appearance of, or sharp increase in, the amount of a fraction “F” migrating faster than albumin and containing large quantities of lipids. The possible significance of these results is discussed.