Abstract
Summary
Hemorrhagic follicles in intra-splenic ovarian grafts in castrated guinea pigs appear irrespectively whether one or 2 ovaries are grafted into the spleen. On the contrary, hemorrhagic follicles fail to appear in an intrasplenic graft of the castrated guinea pig when the second ovary is grafted into the kidney. These experiments give definite evidence that the ovarian control of the hypophyseal gonadotrophic function depends not only, if at all, on consumption of gonadotrophins but certainly also on ovarian hormones which reach the general circulation.
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