Abstract
Summary
Subcutaneous administration of diethylstilbestrol to cockerels caused a marked increase in the concentration of the “readily extractable” cholesterol of the plasma as well as in total cholesterol and neutral fat. Cholesterol feeding exerted a similar effect, but at moderately elevated plasma cholesterol levels the concentration of the “readily extractable” fraction was not as great as when the total cholesterol was raised by the administration of estrogenic substances. However, when the total cholesterol was high, about 700 mg %, practically all of it was present in the “readily extractable” form. Roosters receiving a high fat diet for several weeks usually showed a definite increase in the “readily extractable” fraction without a consistent increase in total cholesterol. When the diet contained 10% soybean lecithin; the concentrations of both the total cholesterol and of the “readily extractable” fraction dropped below those found in animals on the basal diet.
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