Abstract
Summary
(1) Liver fat of young rats on a vit. E-deficient, 10% casein diet was increased 4 percentage points, from 8.7 to 12.7, by the inclusion of alpha tocopheryl acetate in the diet, a highly significant difference statistically. When the diet contained 18% casein, no difference was noted due to supplements of alpha tocopheryl acetate. (2) Dietary treatments did not influence the increase in liver fat 24 hours after CC14 injections, though vit. B12 supplements resulted in more rapid return to normal values. The rate of respiration of liver slice in glucose-Ringers was doubled following CC14 injections. This was substantially inhibited by dietary supplements of vit. E. (3) Choline oxidase activity of the liver was not influenced by dietary vit. E or by CC14 injections into rats, although increased dietary fat level increased the activity of this enzyme system.
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