Abstract
Summary
1. The succinoxidase system, as well as its component enzymes, the -SH enzyme succinic dehydrogenase, and cytochrome oxidase, were determined in rat kidney homogenates within two hours after rats were X-irradiated with 400 r or 800 r. No inhibition of any of the enzymes was found. 2. The metabolism of kidney slices from rats given the above amounts of X-radiation was studied manometrieally with sodium succinate and lithium pyruvate substrates. No statistically significant differences were obtained between the oxidative activities of the kidney slices from the control and irradiated animals. 3. The lack of correlation between certain of the in vivo and in vitro effects of irradiation upon enzyme systems is discussed.
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