Abstract
Summary
Mercurial diuretics administered intravenously in chronic dosage to dogs reduced the glomerular nitration rate as measured by the creatinine clearance. This reduction in glomerular filtration rate was found to be temporary in most dogs that did not have severe symptoms of mercury poisoning.
Thiomerin, when administered intravenously in comparable chronic dosage to the dog, was found to be of higher toxicity than either Mercuhydrin or Merthyl, as indicated by reduced creatinine clearances, and other signs of mercury poisoning.
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