Abstract
Summary
Crude soybean trypsin-inhibitor has been found to prevent digestion of plasma and fibrinogen-thrombin clots by tissues growing in vitro. The presence of antitrypsin retards the normal coagulation of plasma but this inhibition can be overcome by the addition of thrombin. The growth of strain cultures of fibroblast-like cells is somewhat depressed by high concentrations of antitrypsin, but the inhibitory effect can be eliminated by repeated cultivation in antitrypsin. Fresh tissue explants are not as sensitive as strain cultures to this inhibitory action.
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