Abstract
Summary
This paper reports the isolation of a filtrable virus from the feces of patients diagnosed either as non-paralytic poliomyelitis or aseptic meningitis and from 2 patients with “fever of unknown origin.” The agent is similar to that reported by Dalldorf and Sickles1 in producing paralysis with moysitis in newborn mice. The recovery of virus was correlated with the appearance of neutralizing antibodies in the patients' sera. At least two immunological types of the virus exist. The virus was widespread in this country during the summer of 1948 having also been isolated from the sewage of a number of cities and from flies collected in widely separated areas. Subclinical infection may be produced in chimpanzees by oral administration of the virus. A laboratory worker has been accidently infected with the virus.
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