Lymphopenia and the Secretion of Adrenalin. ∗

Abstract

Summary

Hemorrhage (1 cc/100 g body weight) and general excitement (induced by the action of a subconvulsive electrical shock) cause lymphopenia and relative neutrophilia in normal but not in adrenodemedullated rats. Insulin hypoglycemia leading to coma induces a greater lymphopenia in normal than in adrenodemedullated animals. It is concluded that hemorrhage, general excitement and insulin coma cause an increased secretion of adrenalin followed by an increased discharge of adrenocortical hormones. Hypoglycemia seems to induce some increased adrenocortical secretion even in the absence of the adrenal medulla.