Abstract
It is a fairly well established fact that an immunity, or rather a resistance to the growth of a transplantable tumor may be induced in white mice and rats by artificial means. This acquired resistance is of a peculiar type and is not similar to the usual form of the anti-bacterial immunity. Clowes and Baeslack's assertion, that the serum of recovered mice cures cancer in other mice, has received no confirmation. Nor has any other known method of detecting the existence of immunity in an organism met with success in the animals refractory to growth of implanted cancer.
While the best manner of immunizing an animal against tumors consists in a previous unsuccessful inoculation of a tumor, this resistance does not appear to be specific. Ehrlich observed that an animal made resistant to a certain class of tumors, carcinoma for instance, is also resistant to the growth of an implantable sarcoma. Furthermore, a resistance may be artifically induced by previous inoculation of normal tissue of the same species of animals. Michaelis produced such an immunity by injection of normal mouse liver; Bashford by injection of blood or washed blood cells, but not by blood-serum; Schoene with different embryonic tissue; Bridre with liver and spleen.
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