Abstract
Summary
1. From beef stroma pretreated at room temperature with acetone and alcohol, a fraction was isolated with boiling 100% alcohol which, in a dilution of 1:500,000, combines with the sheep blood agglutinin of human serum produced during serum sickness. Using the terminology of Schiff, this fraction corresponds to the heterogenetic serum sickness antigen; it could be separated to a large extent from the heterogenetic mononucleosis antigen which also occurs in beef stroma.
2. The so-called serum sickness antigen also occurs heterogenetically in guinea pig kidney and it could also be isolated from the Forrsman antigen although without increase in activity.
3. Horse serum is a poorer source for isolation of The so-called serum sickness antigen. The latter could be isolated from the serum, after removal of the albumin bodies by coagulation with heat, with an activity of 1:1,500.
Get full access to this article
View all access options for this article.