Abstract
Summary
Desoxyribose nucleoprotein has been identified as a significant constituent of purulent and inflammatory exudates derived from patients. Its chemical characteristics have been described and it has been isolated in quantities ranging from 30 to 70% of the total purulent sediment.
Its physical characteristics of stringiness, viscidity, and coagulated gel, indicate its significance in contributing to the sedimented elements of exudations. Protein-free desoxy-ribonucleic acid has been derived from the nucleoprotein.
The liquefaction of both the nucleoprotein and the nucleic acid has been found to occur following the addition of beef desoxyribonuclease and preparations of hemolytic streptococcal filtrates containing desoxyribonuclease,.
By the Feulgen method of staining the abundance of desoxyribose nucleoprotein in exudates has been demonstrated microscopically.
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