Abstract
Summary
This study indicates that the changes in the excretion of ascorbic acid are not accurate indications of utilization. The ingestion of both salts significantly lowered the mean plasma ascorbic acid content of the subjects indicating an interference with normal utilization. The reduced excretion of ascorbic acid with the ingestion of sodium bicarbonate both daily and in response to a test dose would seem therefore to represent more accurately increased destruction of ascorbic acid in the excretory process; and conversely, the increased excretion with ammonium chloride would seem to represent increased preservation in the excretory process.
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