Abstract
Summary
Canaries were injected intramuscularly with sporozoites of P. cathemerium 3H2 in pooled hen or canary blood, the sporozoite-blood mixtures having been incubated previously at 41.5° C, with agitation, for periods of 1/2, 1, 1 1/2, 2, and 2 1/2 hours. Of 80 canaries injected with sporozoites in canary blood, 97.5% became infected; of 76 canaries injected with sporozoites in hen blood, 2.6% became infected. All 74 canaries which failed to become infected when injected with sporozoites in hen blood did become infected when subsequently bitten by infected mosquitoes. It is felt that these findings suggest the existence of a factor in the blood of the hen that prevents the initiation by the sporo-zoite of the exoerythrocytic cycle in the canary.
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