Abstract
Summary
The incubation of mouse spontaneous carcinoma, rabbit Brown-Pearce carcinoma, and their autologous liver slices with bacterial cultures showed in general that cells of both liver and tumor were uninjured or injured equally. Cultures of Sporosarcina ureae damaged tumor cells and left liver cells histologically unaffected. Evidence was obtained that the selective carcinoclastic factor of S. ureae cultures was contained within the cells and released on autolysis.
We are indebted to Dr. C. B. van Niel of the Hopkins Marine Station for free access to the culture collection, to Colonel Max Levine for cultures of several of the Enterobaeteriaeeae, and to Dr. William Negherbon for cultures of trypanosomes and detailed directions for their maintenance.
Get full access to this article
View all access options for this article.