Abstract
Summary
In growing mice, pantothenic acid is essential for the growth of the skeleton. Deficiency of this vitamin causes inhibition of growth and endochondral ossification. The male reacts more quickly to lack of pantothenic acid than the female. On feeding an adequate stock diet subsequent to a prolonged deficiency, growth of cartilage and ossification are resumed rapidly and may surpass in intensity the processes seen in normal nondeficient animals. In the adult mouse, skeletal changes were not observed under the influence of pantothenic acid deficiency.
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