Abstract
Summary
No diminution in the formation of creatine, as measured by its urinary excretion, was found in animals on a diet deficient in labile methyl groups. The available methionine was preferentially used for growth and creatine formation. The increased excretion of creatine by these animals, apparently associated with weight loss, causes a waste of needed methyl groups instead of their conservation.
Grateful acknowledgment is made to Dr. C. R. Treadwell for his generous advice.
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