Abstract
Summary
d,l-0-Heterobiotin has biotin-like activity for the chick. Levels of 20 γ per 100 g of purified biotin-deficient basal ration give complete protection against dermatitis and some growth response. The growth activity of the oxygen analog varies inversely with the level fed and growth comparable to that on an adequate biotin diet was not obtained. d,l-0-Heterobiotin can be detected in the liver and muscle tissue of chicks fed high amounts of this compound.
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