Abstract
Summary
The antibody response of swine to second vaccination with formalin-inactivated swine influenza virus was greatly influenced by the period between vaccinations. Second vaccination at intervals of one to four weeks resulted in antibody titers and amounts progressively greater in direct relation to the length of the interval. In parallel higher antibody levels were maintained for longer periods in those animals receiving the second vaccination after the longer intervals. Considering the height of titer after the second vaccination, together with the rapid loss of antibody after the first injection, the interval between vaccinations optimum for maintenance of the highest antibody levels appeared to be about three weeks.
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