Abstract
Summary
Rats fed a synthetic diet containing 10% glucoascorbic acid lose weight and develop severe diarrhea. Similar but less severe symptoms develop when 10% ascorbic acid is used. Post-mortem examination revealed no hemorrhages in any part of the body. Animals receiving 2% liver powder in addition to either 10% glucoascorbic acid or ascorbic acid grew as well as normal animals although they showed moderate diarrhea. Glucoascorbic acid at levels of 5, 1 and 0.5% had no effect on the growth of rats but the 5 and 1% levels produced diarrhea.
Chicks fed a synthetic ration containing 10% glucoascorbic acid and 2% solubilized liver showed no deleterious effects.
The severe diarrhea and loss of weight in guinea pigs fed a natural diet containing 10% glucoascorbic acid could not be prevented by the addition of 10% ascorbic acid but was prevented by the addition of 6% 1:20 liver powder.
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