Evidence for Circulating Menstrual “Toxin” During Menstruation and Toxemia of Late Pregnancy

Abstract

Conclusion

Serum from the circulating blood of women during menstruation and toxemia of late pregnancy differs from that of normal non-menstruating and normally pregnant women and resembles menstrual “toxin” in that it is pyrogenic and fibrinolytic, gives positive precipitin tests with the serum of rabbits immunized against cannie “necrosin,” and contains a pseudoglobulin capable of prolonging the survival time of rats after a lethal dose of menstrual toxin. It is concluded that a factor identical to menstrual “toxin” is present in the circulating blood of menstruating and toxemic women. The protective factor is being further investigated as to its possible therapeutic applications.