Germicidal Potency and Tissue Toxicity of Surface Active Saline Mixture of Azochloramid

Abstract

Conclusions

The addition of sodium tetradecyl sulfate to Azochloramid increased the efficiency of the germicide for Staphylococcus aureus and decreased it for Eberthella typhosa. Since Staphylococcus aureus is likely to be the better test organism it may be concluded that the addition of wetter probably improved the germicidal efficiency of Azochloramid. Certainly the addition of wetter greatly improved Azochloramid by decreasing the concentration required to produce the same effect as germicide without wetter. This results in a considerably more potent and economical preparation.

For purposes of comparison all germicides tested to date are included in Table II. The halogens gave the lowest toxicity indexes when tested against both Staphylococcus aureus (Gram positive) and Eberthella typhosa (Gram negative). Since Staphylococcus aureus is likely to be the better test organism the halogens were followed by the phenols, the silver compounds, the mercurials, and lastly the dyes in the order named.