Abstract
Summary
The same daily doses of purified lactogenic hormone (60 I.U.) and estrone (10 I.U.) capable of inducing beginning lobulo-alveolar mammary growth in the hypophysec-tomized rat, also ensured successful implantation in rats hypophysectomized and injected from the day of sperm. Since only about one-half of the estimated number of implantations were found to have developed normally through mid-pregnancy it follows that these 2 pure substances in the doses used did not adequately substitute for the intact pituitary of a pregnant rat. When injected alone neither lactogenic hormone nor estrone permitted implantation to occur.
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