Abstract
Summary
Calcium pantothenate stimulates growth and prevents pattern graying (but not stippling) in filtrate factor deficient rats. The requirement for growth is less than for the prevention of pattern graying. Black rats receiving Ca pantothenate either pro-phylactically or curatively have stippled fur.
A liver filtrate stimulates growth to a greater extent than does Ca pantothenate and completely protects against graying. It would thus appear that pantothenic acid does not completely replace liver filtrate.
A concentrate prepared by the continuous extraction of cane molasses with ether both stimulated growth and prevented graying while a chloroform extract prepared from it was without activity.
Inositol added to Ca pantothenate does not significantly improve the results obtained with calcium pantothenate alone.
Rats maintained on a 24% casein diet apparently have no need for choline.
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