Abstract
Conclusions and Comments
The tissue of the pars nervosa in its entirety plus that of the ventral extent of the hypothalamus is not essential for the maintenance of a normal fluid exchange in the cat. Therefore, unless a tissue of the adenohypophysis secretes the anti-diuretic principle, tissue elsewhere (hypothalamus) must possess this power. This conclusion is predicated on the assumptions, first, that these experiments were not complicated by as yet unrecognized factors, and, second, that a continuous elaboration of the antidiuretic substance is invariably essential for the maintenance of a normal fluid exchange.
If the adenohypophysis is concerned the pars tuberalis as well as the pars intermedium possess antidiuretic secretory powers since: (1) total hypophysectomy except for remnant of tuberalis, 9 and (2) removal of the entire tuberalis and most of the pars anterior, leaving the isolated posterior lobe, can be accomplished without precipitating d. i.
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