Abstract
Summary and Conclusions
Each of 3 adult female rabbits, 8 1/2-15 1/2 months of age, was injected subcutaneously with testosterone propionate, 1 mg per day. Masculinization of the external genitalia followed in about 2 weeks, the clitoris enlarging to form a structure i esembling a hypospadic penis, and the labia fusing to partially close the vaginal opening. The anatomical modifications were reversible when treatment was suspended. The psycho-sexual behavior of treated animals became masculine in character. The same response to treatment with respect to somatic sexual characters and psycho-sexual behavior was also induced in a spayed adult female rabbit.
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