Abstract
Conclusion
Artificially induced fever within therapeutic limits destroys lymphocytes and inhibits lymphopoiesis in the normal experimental animal, while at the same time resulting in an increase and extension of marrow myelopoiesis, tissue clasmatocytosis and peripheral granulocytic leucocytosis. The character and nature of this profound effect of fever upon the cellular equilibria may indicate an accessory role in the strengthening or weakening of the body defenses—depending upon the particular circumstance—and should be considered whenever artificial hyperpyrexia is contemplated as a means of treating human disease.
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