Abstract
The relations of the gastric secretion to the salivary glands are illustrated by the following clinical and experimental observations:
1. In four cases of Mikulicz's disease with normal conditions of the blood the stomach was found to secrete no gastric juice during the course of the disease. Mikulicz's disease consists in a benign chronic swelling of all the salivary and lacrimal glands.
2. In dogs with accessory stomachs (Pawlow) the removal of all the salivary glands abolishes permanently all gastric secretion.
3. The gastric secretion is not started in such dogs by feeding them with food masticated and well insalivated by other normal dogs.
4. The abolished gastric secretion is temporarily resumed by peritoneal or intravenous injections of extracts made of salivary glands of normal dogs.
5. This temporary resumption takes place even if the stomach be completely isolated from the central nervous system.
These observations justify the conclusion that normal gastric secretion depends upon the internal secretion of the salivary glands.
Get full access to this article
View all access options for this article.