Studies on Reduced Ascorbic Acid Content of the Blood Plasma. ∗

Abstract

Summary

Experimental data is presented confirming the work of Farmer and Abt that the reduced ascorbic acid content of the blood plasma in the “normal” individual parallels the vitamin C intake. Confirmation of this is presented in a controlled dietary experiment using rhesus monkeys. For satisfactory comparative data, determinations should be made on fasting blood specimens. On the basis of the studies recorded, we believe that fasting plasma ascorbic acid levels below 0.7 mg. % are probably sub-optimal. Levels langing between 0.7 and 0.9 mg. % would appear adequate. Optimal levels probably lie above this range. Reduced ascorbic acid plasma levels below 0.5 mg. % must be considered low.†