Abstract
The blood picture in experimental mammals infected with S. mansoni shows first a leukocytosis, paralleling the migration of the larvae through the lungs. This is followed by a gradually developing leukopenia, with or without an eosinophilia, which, if present, is most pronounced about the end of the prepatent period. From about the 40th day there is an excess of euglobulin in the blood plasma. Moderate to late clinical cases usually give a positive precipitation test for serum globulin. The total erythrocyte counts are little altered in experimental and clinical cases, but there is definite evidence of regeneration of these cells, as indicated by a hyperplastic bone marrow and an increased reticulocyte count.
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