“The action of eosin and erythrosin upon snake venom,” with demonstrations

Abstract

The hemolytic principles of venom react differently to eosin depending upon their native labilities. The hemolysin of Crotalus venom suffers most; that of Daboia next, while that of Cobra is the most resistant.

The toxicity of different venoms is more or less diminished by eosin in the light. Cobra is least affected; Crotalus and Daboia venoms are most affected. Crotalus venom loses its toxicity chiefly by destruction of hemorrhagin, and Daboia by destruction of coagulin.

Neurotoxin is little or not at all affected by eosin or erythrosin.

There is a parallel between the susceptibility of the toxic principles of snake venom to fluorescent anilins and to other injurious influences. Hemorrhagin and coagulin are less stable at high temperatures than neurotoxin, and more easily destroyed by acids than neurotoxin and hematoxin.