Abstract
Conclusions
Certain colloidal dyes, namely, congo red, vital red, trypan red, mercurochrome, rose bengal and sodium fluorescein, strikingly prevent the heat-coagulation and mercuric-precipitation of horse serum and egg albumin, and also the alkaloidal precipitation by Mayer's reagent. These powerful protective actions in vitro appear to be associated with the physical (colloidal) properties of these dyes, in agreement with a similar mechanism of protection exerted by some of these dyes on the actions of potent toxins and drugs in vitro. The possible significance of the mechanism of these common protective phenomena, for chemotherapy in general, is briefly discussed.
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