Abstract
Summary
Comparative oral toxicity studies on guinea pigs, rabbits, and cats, and a comparative protozoacidal evaluation on amebae ifzvitro as well as on natural balantidial infestations in guinea pigs and on natural monkey amebiasis indicates that 4-carbamino-phenyl-arsonic acid (“carbarsone”) has definite advantages from the standpoint of application to anti-amebic therapy over acetarsone (“stovarsol”), tryparsamide, “proparsamide,” “iso-butarsamide,” and “n-butarsamide.” It is definitely less toxic on oral administration than these compounds and seems generally more protozoacidal in tolerated doses.
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