Abstract
The effects of subcutaneous injections of ephedrine on blood lactic acid and sugar plasma fat were studied in 10 dogs varying in weight from 4 to 18 kilos. The animals were in a post-absorptive condition and under the influence of amytal. The dosage of ephedrine sulphate (Eli Lilly and Company) in the different experiments varied from 1/4 to 1 cc. of a 3% solution, and was given every 15 minutes for from 2 to 5 hours.
The level of blood sugar was raised in every experiment. Increases in fat occurred in 7 experiments and therefore were not so consistent as those obtained with adrenalin. 1 The concentration of the lactic acid of the blood increased in only 5 experiments. The determination of the total solids of the plasma was unsatisfactory because of hemolysis, an effect of ephedrine. The results of a typical experiment are presented below.
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