Abstract
A destructive lesion was placed in the left lenticular nucleus of forty cats. These animals were allowed to live from 9 to 11 days and their symptoms carefully observed. The 15 brains containing the best lesions were then prepared by the Marchi method for degenerated nerve fibers.
The following efferent fiber systems were found to have their origin in the globus pallidus:
1. A lateral strio-bulbar fasciculus, closely associated with the lateral cortico-bulbar tract, is composed of (a) a primary, homolateral division to the masticator, facial and ambiguous nuclei; (b) a secondary division to the trochlear, abducens, and hypoglossal nuclei of both sides; (c) a crossed division decussating with the brachium conjunctivum to reach the masticator, facial and ambiguous nuclei of the opposite side.
2. A strio-tegmental fasciculus terminates in the interstitial nucleus of Cajal, the nucleus of Darkschewitsch, and the oculomotor nucleus of the homolateral and perhaps also of the opposite side.
3. A large fasciculus of fibers terminates in the intrapeduncular nucleus of Malone (motor division of the substantia nigra), and the peripeduncular nucleus of Jacobsohn.
4. A group of fibers passes to the anterior, and another to the posterior part of the substantia reticularis hypothalami of Malone (nucleus of Forel's field) of the homolateral side.
5. Many fibers terminate in the subthalamic nucleus of Luys.
6. Many fibers pass to cells in the region medial to Forel's field h2 (Mammilo-infundibular nucleus of Malone), of the same and opposite sides.
7. Fibers pass through Meynerts commissure to the globus pallidus and a few to the region of Forel's field H2 of the opposite side.
These fiber systems are identical with those found in a study of seven human brains with degeneration in the lenticular nuclei.
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