Heavy alcoholization and prenatal mortality in mice.

Abstract

Summary

Brief reference is made to the more important earlier studies on the action of a utero-stimulating substance in mammals.

In a small group of tests of the utero-stimulating action of a placental extract, and of a substance prepared from the liquor folliculi of the sow by the Allen-Doisy method, we have obtained a few positive results-enlargement and hyperemia of the oviduct of virgin doves. This supplies the last necessary fact in proof of the lack of specificity, as between birds and mammals, of this substance.

Heavy dosage failed to affect a response in the virgin oviduct in some cases. Responses in the ovary and on sex behavior in virgin and mature doves have not been observed. An insufficient number of cases was studied but our results indicate a less ready, and a less varied, response of the bird to this substance than has been found for mammals.