Abstract
Abstract
The purpose of this study was to compare the effects of pancreastatin (PST) (400 pmol/kg/hr) and somatostatin (SRIF) (400 pmol/kg/hr) on food-induced release of gastrin, pancreatic polypeptide (PP), and peptide YY (PYY) in conscious dogs. The present findings indicate that SRIF is more potent than PST on the inhibition of food-induced release of PP; that SRIF and PST do not influence food-induced release of gastrin; and that PST cannot inhibit food-induced release of PYY, whereas SRIF inhibits PYY release in a potent fashion.
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