Abstract
Most of the literature concerning the action of the citrates, malates, phosphates deals with the toxicity, tolerance, excretion and cumulative effects of these substances. The experiments briefly presented in this paper were carried out to ascertain whether the repeated administration of various acid radicals, commonly classified as “calcium precipitants,” would, (1) result in a permanent decrease of the calcium content of the blood and, (2) if the calcium balance would be affected in any way.
Rabbits receiving a calcium-rich diet (daily intake of 0.44-1.24 gm. of Ca 1 were used as experimental animals. The calcium balance was determined at weekly intervals; the calcium content of the whole blood and plasma at intervals of 3-7 days.
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