Inhibition of Viral Replication in Cell Cultures Treated with Prostaglandin E 1 1

Abstract

Abstract

A study has been initiated to determine the influence of prostaglandins on virus replication and its relationship to the interferon system. In the present study, data are presented which show that pretreatment of cells in culture with prostaglandin E₁ results in (i) a reduction in the yields of Mengo, MM and polio viruses, (ii) enhanced yields of interferon, and (iii) inhibition of cell division.