Abstract
These curves were obtained by feeding normal males colored, with 100 grams of the pure sugar, on a fasting stomach. The dose was as a rule given after the first sample of blood had been taken; this was as a rule at 8 A.M. The second, third and fourth samples were taken one, two and three hours after the ingestion of the sugar, which had been dissolved in a large glass of water.
The urines were tested for glucose up to three hours after the last sample of blood had been taken, and in none of the cases did a specimen ever show the slightest trace of a reducing substance with Benedict's qualitative solution.
The glucose curve was that with which all are familiar, that is rising to its highest point one hour after the ingestion, and then dropping to the normal at the end of the next hour or two.
Maltose gave the same curve as the glucose. Mannite gave the same time curve as the glucose, and maltose, but did not rise to the same height as the other two; the average of five cases gave an increase of only 10 milligrams per IOO C.C. of blood, while that for glucose was 40 milligrams, and for maltose 34 milligrams.
Cane sugar showed a curve that reached its height at the end of the second hour after its ingestion, and had dropped to normal at the third hour. Its average rise for 10 cases was 20 milligrams per IOO C.C. of blood. Lactose shows only a very slight rise, 4 milligrams, and that at the end of the second hour, as was the case with the other disachrade, cane sugar. I have been unable to consult the literature and so will offer- the figures for what they are worth.
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