Abstract
Summary
The effects of renal nerve stimulation (RNS) and norepinephrine infusion (NE) on the intrarenal distribution of renal blood flow were studied in the isolated blood-perfused kidney. Both RNS and NE caused a redistribution of fractional blood flow from the inner half to the outer half of the renal cortex. Both vasoconstrictor stimuli resulted in a relatively greater vasocon-striction of the inner cortical vasculature. It is concluded that the inner cortical vasculature is more responsive to vasoactive stimuli and is the important locus for regulation of the distribution of renal cortical blood flow.
The authors wish to thank the staff of Allen Bradley Medical Science Laboratory for their help in completing this project.
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