Abstract
Summary
A previously reported (1) hamster monolayer cell culture derived from a fibro-hemangiosarcoma was grown on firm gels of reconstituted collagen. The gel was cleared without concomitant collagenolysis as judged by the release of labeled soluble collagen peptides from the reconstituted gel. In the final phase, the collagen was condensed. Histological examination of the condensed gel revealed a proliferation of cells showing variations in cell appearance within the gel matrix.
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