Abstract
Summary
A guinea pig C-type virus was successfully isolated from primary and passaged cells derived from leukemic and normal strain 2, and strain 2-Hartley hybrid guinea pigs. Activation of the virus required BUDR treatment. Morphologically, both in infected cells and in negatively stained preparations, the guinea pig C-type virus resembles other members of the C-type virus group. Purified guinea pig C-type virus labeled with 3H-uridine had an equilibrium density of 1.17 ± 0.01 g/ml in sucrose.
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