Abstract
Summary
C3H/HeJ mouse lymphoid cells treated with Vibrio cholerae neuraminidase (VCN) are more easily lysed by normal rabbit, normal guinea pig, and normal human sera than are untreated cells or cells exposed to heat-inactivated VCN.
Absorption studies suggest that VCN does not unmask a greater number of previously available xenogeneic specificities on the cell surface. Instead, VCN appears to unmask new antigens for which preformed antibodies also exist in xenogeneic sera.
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