Abstract
Summary
Experiments were performed in order to investigate the mode of action of glutaraldehyde in the prolongation of skin grafts. 1. Glutaraldehyde-incubated grafts had prolonged survival (35 days) when compared to untreated controls (15.5 days). 2. Glutaraldehyde-treated isografts were destroyed at 95 days. 3. Glutaraldehyde-treated second isografts were also destroyed at 3 months. 4. Histologic examination of glutaraldehyde-treated grafts showed a bizarre, poorly vascularized, poorly defined histology, probably incompatible with viability.
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