Abstract
Summary
Effects of dietary chloride, with and without sodium, in potassium-deficient rats were studied in two experiments with similar results. The rats were sacrificed after five weeks on the experimental diets. Exclusion of chloride from potassium-deficient diets modified some of the histological findings in the potassium-deficient rats. Renal lesions were much less pronounced, but hearts were abnormally heavy when chloride was omitted. Testes were normal in the presence of chloride but markedly atrophic in its absence. Potassium obliterated these effects of chloride deficiency.
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