Abstract
If the lungs of an anaphylactic guinea pig are repeatedly perfused with dilute foreign protein, either in Locke's solution or in 50 per cent. normal blood, the lungs are thrown into a typical anaphylactic response.
Quantitative titrations of the perfusion fluid, by means of a specific precipitating serum, show no recognizable changes in the amount of protein as a result of the repeated passages through the lungs.
The titrations therefore furnish no support, either for the sessile receptor hypothesis of Ehrlich, or for the protein-destruction theory of Vaughan.
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