Abstract
Summary
A sex difference was observed in the metabolism of hexobarbital in the Mongolian gerbil. The hexobarbital hydroxylating activity of the liver microsomal enzymes and the microsomal content of cytochrome P-450 were found to be higher in the female gerbils. This was further supported by the finding that the duration of hexobarbital hypnosis was shorter in the female than in the male gerbils.
Get full access to this article
View all access options for this article.