Abstract
Summary
Bone marrow and spleen cells were transplanted from normal mice to lethally irradiated recipient mice. Comparable numbers of splenic surface colonies were formed from 105 marrow or 106 spleen cells. However, more splenic megakaryocytes were produced by stem cells from spleen than marrow. This finding indicates that there is an intrinsic difference between stem cells in the marrow and those in the spleen of normal mice.
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