Abstract
Summary
When human blood was drawn into a syringe containing heparin and pumped through a column of glass beads, over 90% of the platelets were retained. Platelet retention was markedly reduced if the blood was first disturbed by inversion in a tube, slow centrifugation and remixing, or rapid back-and-forth transfer between two plastic or glass syringes. Retention was restored within 1 hr after the last-named maneuver but could be reduced again by redisturbing the blood. The high platelet retention noted when blood inverted in a tube was passed through columns prepared in Bowie's laboratory indicates the marked effect of the plastic tubing and beads.
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